A phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B(12) in Japanese patients with solid tumours

The purpose of this study was to determine the maximum tolerated dose (MTD) and recommended dose (RD) of pemetrexed with folate and vitamin B12 supplementation (FA/VB(12)) in Japanese patients with solid tumours and to investigate the safety, efficacy, and pharmacokinetics of pemetrexed. Eligible pa...

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Detalles Bibliográficos
Autores principales: Nakagawa, K, Kudoh, S, Matsui, K, Negoro, S, Yamamoto, N, Latz, J E, Adachi, S, Fukuoka, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360511/
https://www.ncbi.nlm.nih.gov/pubmed/16940981
http://dx.doi.org/10.1038/sj.bjc.6603321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360511/
https://www.ncbi.nlm.nih.gov/pubmed/16940981
http://dx.doi.org/10.1038/sj.bjc.6603321

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