The role of MYH and microsatellite instability in the development of sporadic colorectal cancer

Biallelic germline mutations in MYH are associated with colorectal neoplasms, which develop through a pathway involving somatic inactivation of APC. In this study, we investigated the incidence of the common MYH mutations in an Australian cohort of sporadic colorectal cancers, the clinicopathologica...

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Detalles Bibliográficos
Autores principales: Colebatch, A, Hitchins, M, Williams, R, Meagher, A, Hawkins, N J, Ward, R L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360566/
https://www.ncbi.nlm.nih.gov/pubmed/17031395
http://dx.doi.org/10.1038/sj.bjc.6603421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360566/
https://www.ncbi.nlm.nih.gov/pubmed/17031395
http://dx.doi.org/10.1038/sj.bjc.6603421

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