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The role of MYH and microsatellite instability in the development of sporadic colorectal cancer
Biallelic germline mutations in MYH are associated with colorectal neoplasms, which develop through a pathway involving somatic inactivation of APC. In this study, we investigated the incidence of the common MYH mutations in an Australian cohort of sporadic colorectal cancers, the clinicopathologica...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360566/ https://www.ncbi.nlm.nih.gov/pubmed/17031395 http://dx.doi.org/10.1038/sj.bjc.6603421 |