The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens

We used SEREX technology to identify novel tumour-associated antigens in patients with primary hepatocellular carcinoma and found serological responses to the polycomb group (PcG) protein BMI-1, which is overexpressed in a range of different tumour types. Further studies identified T-cell responses...

Descripción completa

Detalles Bibliográficos
Autores principales: Steele, J C, Torr, E E, Noakes, K L, Kalk, E, Moss, P A, Reynolds, G M, Hubscher, S G, van Lohuizen, M, Adams, D H, Young, L S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360579/
https://www.ncbi.nlm.nih.gov/pubmed/17024127
http://dx.doi.org/10.1038/sj.bjc.6603369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360579/
https://www.ncbi.nlm.nih.gov/pubmed/17024127
http://dx.doi.org/10.1038/sj.bjc.6603369

Ejemplares similares