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The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens

We used SEREX technology to identify novel tumour-associated antigens in patients with primary hepatocellular carcinoma and found serological responses to the polycomb group (PcG) protein BMI-1, which is overexpressed in a range of different tumour types. Further studies identified T-cell responses...

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Detalles Bibliográficos
Autores principales:	Steele, J C, Torr, E E, Noakes, K L, Kalk, E, Moss, P A, Reynolds, G M, Hubscher, S G, van Lohuizen, M, Adams, D H, Young, L S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360579/ https://www.ncbi.nlm.nih.gov/pubmed/17024127 http://dx.doi.org/10.1038/sj.bjc.6603369

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