Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells

Activation of the type I insulin-like growth factor receptor (IGF-IR) regulates several aspects of the malignant phenotype, including cancer cell proliferation and metastasis. Phosphorylation of adaptor proteins downstream of IGF-IR may couple IGF action to specific cancer phenotypes. In this study,...

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Detalles Bibliográficos
Autores principales: Byron, S A, Horwitz, K B, Richer, J K, Lange, C A, Zhang, X, Yee, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360584/
https://www.ncbi.nlm.nih.gov/pubmed/17043687
http://dx.doi.org/10.1038/sj.bjc.6603354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360584/
https://www.ncbi.nlm.nih.gov/pubmed/17043687
http://dx.doi.org/10.1038/sj.bjc.6603354

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