11q13 amplification status and human papillomavirus in relation to p16 expression defines two distinct etiologies of head and neck tumours

Two distinct etiologies of head and neck squamous cell carcinoma (HNSCC) have been proposed, DNA damage owing to tobacco and alcohol exposure and human papillomavirus (HPV) oncogene-mediated transformation. Common genetic alterations in HNSCC include TP53 mutations, 11q13 amplification (amp) and CDK...

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Detalles Bibliográficos
Autores principales: Ragin, C C R, Taioli, E, Weissfeld, J L, White, J S, Rossie, K M, Modugno, F, Gollin, S M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360598/
https://www.ncbi.nlm.nih.gov/pubmed/17003776
http://dx.doi.org/10.1038/sj.bjc.6603394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360598/
https://www.ncbi.nlm.nih.gov/pubmed/17003776
http://dx.doi.org/10.1038/sj.bjc.6603394

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