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Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity

Overexpression and/or activity of c-Src non-receptor tyrosine kinase is associated with progression of several human epithelial cancers including breast cancer. c-Src activity in ‘pure’ ductal carcinoma in situ (DCIS) was measured to assess whether this predicts recurrence and/or correlates with HER...

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Detalles Bibliográficos
Autores principales: Wilson, G R, Cramer, A, Welman, A, Knox, F, Swindell, R, Kawakatsu, H, Clarke, R B, Dive, C, Bundred, N J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360601/
https://www.ncbi.nlm.nih.gov/pubmed/17060931
http://dx.doi.org/10.1038/sj.bjc.6603444