CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding

In order to identify potential markers of renal cancer, the plasma membrane protein content of renal cell carcinoma (RCC)-derived cell lines was annotated using a proteomics process. One unusual protein identified at high levels in A498 and 786-O cells was CD70 (TNFSF7), a type II transmembrane rece...

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Detalles Bibliográficos
Autores principales: Adam, P J, Terrett, J A, Steers, G, Stockwin, L, Loader, J A, Fletcher, G C, Lu, L-S, Leach, B I, Mason, S, Stamps, A C, Boyd, R S, Pezzella, F, Gatter, K C, Harris, A L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360640/
https://www.ncbi.nlm.nih.gov/pubmed/16892042
http://dx.doi.org/10.1038/sj.bjc.6603222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360640/
https://www.ncbi.nlm.nih.gov/pubmed/16892042
http://dx.doi.org/10.1038/sj.bjc.6603222

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