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Cigarette smoking, von Hippel–Lindau gene mutations and sporadic renal cell carcinoma

We investigated whether smoking is associated with mutations in the Von Hippel–Lindau (VHL) gene in 337 cases of sporadic renal cell carcinoma (RCC) among 120 852 people followed for 11.3 years; the findings suggest that smoking causes RCC independently of VHL gene mutations.

Detalles Bibliográficos
Autores principales: van Dijk, B A C, Schouten, L J, Oosterwijk, E, Hulsbergen-van de Kaa, C A, Kiemeney, L A L M, Goldbohm, R A, Schalken, J A, van den Brandt, P A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360644/
https://www.ncbi.nlm.nih.gov/pubmed/16892044
http://dx.doi.org/10.1038/sj.bjc.6603281