Cargando…

Role of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells

Testicular germ cell tumour (TGCT) is the most common malignancy in young males. Although most TGCTs are sensitive to cisplatin-based chemotherapy, significant numbers of TGCT patients still relapse and die each year because of the development of resistance to cisplatin. Previously, we first reporte...

Descripción completa

Detalles Bibliográficos
Autores principales: Fung, M K L, Cheung, H-W, Ling, M-T, Cheung, A L M, Wong, Y-C, Wang, X
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360662/
https://www.ncbi.nlm.nih.gov/pubmed/16880791
http://dx.doi.org/10.1038/sj.bjc.6603284