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Role of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells

Testicular germ cell tumour (TGCT) is the most common malignancy in young males. Although most TGCTs are sensitive to cisplatin-based chemotherapy, significant numbers of TGCT patients still relapse and die each year because of the development of resistance to cisplatin. Previously, we first reporte...

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Detalles Bibliográficos
Autores principales:	Fung, M K L, Cheung, H-W, Ling, M-T, Cheung, A L M, Wong, Y-C, Wang, X
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360662/ https://www.ncbi.nlm.nih.gov/pubmed/16880791 http://dx.doi.org/10.1038/sj.bjc.6603284

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