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Evaluations of biomarkers associated with 5-FU sensitivity for non-small-cell lung cancer patients postoperatively treated with UFT

The sensitivity to 5-fluorouracil (5-FU) has been reported to be associated with target molecule thymidylate synthase (TS), fluoropyrimidine-metabolising enzymes such as orotate phosphoribosyltransferase (OPRT), and dihydropyrimidine dehydrogenase (DPD). We performed an immunohistochemical study on...

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Detalles Bibliográficos
Autores principales: Nakano, J, Huang, C, Liu, D, Masuya, D, Nakashima, T, Yokomise, H, Ueno, M, Wada, H, Fukushima, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360692/
https://www.ncbi.nlm.nih.gov/pubmed/16880781
http://dx.doi.org/10.1038/sj.bjc.6603297