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Case–control, kin-cohort and meta-analyses provide no support for STK15 F31I as a low penetrance colorectal cancer allele

Recently, homozygosity for T91A single-nucleotide polymorphism (SNP) in the serine/threonine kinase (STK15) gene, which generates the substitution F31I has been proposed to increase the risk of a number of tumours including colorectal cancer (CRC). To further evaluate the relationship between STK15...

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Detalles Bibliográficos
Autores principales: Webb, E L, Rudd, M F, Houlston, R S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360710/
https://www.ncbi.nlm.nih.gov/pubmed/17003782
http://dx.doi.org/10.1038/sj.bjc.6603382