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Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa
The epidermal growth factor receptor (EGFr) is considered a major target for treatment of colorectal cancer (CRC). We found a mean EGFr content significantly lower but more activated in colonic neoplastic tissue than in paired normal mucosa. Phosphorylated (pY1068) EGFr detection in CRC may be a bet...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360732/ https://www.ncbi.nlm.nih.gov/pubmed/17088913 http://dx.doi.org/10.1038/sj.bjc.6603441 |