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Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa

The epidermal growth factor receptor (EGFr) is considered a major target for treatment of colorectal cancer (CRC). We found a mean EGFr content significantly lower but more activated in colonic neoplastic tissue than in paired normal mucosa. Phosphorylated (pY1068) EGFr detection in CRC may be a bet...

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Detalles Bibliográficos
Autores principales:	Piazzi, G, Paterini, P, Ceccarelli, C, Pantaleo, M A, Biasco, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360732/ https://www.ncbi.nlm.nih.gov/pubmed/17088913 http://dx.doi.org/10.1038/sj.bjc.6603441

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