Cancer biology: mechanism of antitumour action of vorinostat (suberoylanilide hydroxamic acid), a novel histone deacetylase inhibitor

Histone deacetylase (HDAC) inhibitors represent a potential new class of antitumor agents. Vorinostat (suberoylanilide hydroxamic acid or SAHA) is a potent inhibitor of HDAC activity and has undergone initial evaluation in several Phase I and II clinical trials. HDACs are enzymes that catalyse the r...

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Detalles Bibliográficos
Autor principal: Richon, V M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360770/
http://dx.doi.org/10.1038/sj.bjc.6603463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360770/
http://dx.doi.org/10.1038/sj.bjc.6603463

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