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Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence

In lung cancer cyclooxygenase-2 (COX-2) expression has been reported to stabilise survivin, an inhibitor of apoptosis (IAP) which prevents cell death by blocking activated caspases. COX-2 expression limits the ubiquitination of survivin, protecting it from degradation. To determine if COX-2 expressi...

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Detalles Bibliográficos
Autores principales: Barnes, N, Haywood, P, Flint, P, Knox, W F, Bundred, N J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361101/
https://www.ncbi.nlm.nih.gov/pubmed/16421596
http://dx.doi.org/10.1038/sj.bjc.6602932