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Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence
In lung cancer cyclooxygenase-2 (COX-2) expression has been reported to stabilise survivin, an inhibitor of apoptosis (IAP) which prevents cell death by blocking activated caspases. COX-2 expression limits the ubiquitination of survivin, protecting it from degradation. To determine if COX-2 expressi...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361101/ https://www.ncbi.nlm.nih.gov/pubmed/16421596 http://dx.doi.org/10.1038/sj.bjc.6602932 |