Cargando…
Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence
In lung cancer cyclooxygenase-2 (COX-2) expression has been reported to stabilise survivin, an inhibitor of apoptosis (IAP) which prevents cell death by blocking activated caspases. COX-2 expression limits the ubiquitination of survivin, protecting it from degradation. To determine if COX-2 expressi...
Autores principales: | Barnes, N, Haywood, P, Flint, P, Knox, W F, Bundred, N J |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361101/ https://www.ncbi.nlm.nih.gov/pubmed/16421596 http://dx.doi.org/10.1038/sj.bjc.6602932 |
Ejemplares similares
-
Expression of survivin and its splice variants survivin-2B and survivin-ΔEx3 in breast cancer
por: Ryan, B, et al.
Publicado: (2005) -
COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ
por: Boland, G P, et al.
Publicado: (2004) -
A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR/ANZ DCIS trial
por: Pinder, S E, et al.
Publicado: (2010) -
Molecular subtyping of DCIS: heterogeneity of breast cancer reflected in pre-invasive disease
por: Clark, S E, et al.
Publicado: (2011) -
Survivin, Survivin-2B, and Survivin-deItaEx3 expression in medulloblastoma: biologic markers of tumour morphology and clinical outcome
por: Fangusaro, J R, et al.
Publicado: (2005)