mTOR signaling: implications for cancer and anticancer therapy

Mounting evidence links deregulated protein synthesis to tumorigenesis via the translation initiation factor complex eIF4F. Components of this complex are often overexpressed in a large number of cancers and promote malignant transformation in experimental systems. mTOR affects the activity of the e...

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Detalles Bibliográficos
Autores principales: Petroulakis, E, Mamane, Y, Le Bacquer, O, Shahbazian, D, Sonenberg, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361102/
https://www.ncbi.nlm.nih.gov/pubmed/16404421
http://dx.doi.org/10.1038/sj.bjc.6602902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361102/
https://www.ncbi.nlm.nih.gov/pubmed/16404421
http://dx.doi.org/10.1038/sj.bjc.6602902

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