Characterisation of the GRAF gene promoter and its methylation in patients with acute myeloid leukaemia and myelodysplastic syndrome

We report the isolation of the 5′ flanking region of GRAF (GTPase regulator associated with the focal adhesion kinase), previously described as a putative tumour suppressor gene of acute myelogenous leukaemia and myelodysplastic syndrome, and demonstrate its promoter activity in reporter gene assays...

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Detalles Bibliográficos
Autores principales: Bojesen, S E, Ammerpohl, O, Weinhäusl, A, Haas, O A, Mettal, H, Bohle, R M, Borkhardt, A, Fuchs, U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361128/
https://www.ncbi.nlm.nih.gov/pubmed/16404424
http://dx.doi.org/10.1038/sj.bjc.6602939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361128/
https://www.ncbi.nlm.nih.gov/pubmed/16404424
http://dx.doi.org/10.1038/sj.bjc.6602939

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