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Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted

Tumours ferment glucose to lactate even in the presence of oxygen (aerobic glycolysis; Warburg effect). The pentose phosphate pathway (PPP) allows glucose conversion to ribose for nucleic acid synthesis and glucose degradation to lactate. The nonoxidative part of the PPP is controlled by transketola...

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Detalles Bibliográficos
Autores principales: Langbein, S, Zerilli, M, zur Hausen, A, Staiger, W, Rensch-Boschert, K, Lukan, N, Popa, J, Ternullo, M P, Steidler, A, Weiss, C, Grobholz, R, Willeke, F, Alken, P, Stassi, G, Schubert, P, Coy, J F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361175/
https://www.ncbi.nlm.nih.gov/pubmed/16465194
http://dx.doi.org/10.1038/sj.bjc.6602962