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Promoter methylation of P16, RARβ, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing

Methylation profiling of cancer tissues has identified this mechanism as an important component of carcinogenesis. Epigenetic silencing of tumour suppressor genes through promoter methylation has been investigated by a variety of means, the most recent of which is pyrosequencing. We have investigate...

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Detalles Bibliográficos
Autores principales: Shaw, R J, Liloglou, T, Rogers, S N, Brown, J S, Vaughan, E D, Lowe, D, Field, J K, Risk, J M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361183/
https://www.ncbi.nlm.nih.gov/pubmed/16449996
http://dx.doi.org/10.1038/sj.bjc.6602972