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Reduced Secretion of YopJ by Yersinia Limits In Vivo Cell Death but Enhances Bacterial Virulence

Numerous microbial pathogens modulate or interfere with cell death pathways in cultured cells. However, the precise role of host cell death during in vivo infection remains poorly understood. Macrophages infected by pathogenic species of Yersinia typically undergo an apoptotic cell death. This is du...

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Detalles Bibliográficos
Autores principales: Brodsky, Igor E., Medzhitov, Ruslan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361194/
https://www.ncbi.nlm.nih.gov/pubmed/18483548
http://dx.doi.org/10.1371/journal.ppat.1000067