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Clinicopathological significance of mitochondrial D-Loop mutations in head and neck carcinoma

Mitochondrial DNA mutations have been reported in several types of tumours, including head and neck squamous cell carcinoma (HNSCC). The noncoding region of the Displacement-Loop (D-Loop) has emerged as a mutational hotspot and we recently found that they were associated with prognosis and response...

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Detalles Bibliográficos
Autores principales: Lièvre, A, Blons, H, Houllier, A M, Laccourreye, O, Brasnu, D, Beaune, P, Laurent-Puig, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361200/
https://www.ncbi.nlm.nih.gov/pubmed/16495928
http://dx.doi.org/10.1038/sj.bjc.6602993