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A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer

The purpose of this study was to evaluate the safety and activity of fixed-dose capecitabine in patients with advanced colorectal cancer and to correlate pretreatment plasma concentrations of homocysteine and serum and red cell folate with toxicity. Patients received capecitabine 2000 mg (4 × 500 mg...

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Detalles Bibliográficos
Autores principales: Sharma, R, Rivory, L, Beale, P, Ong, S, Horvath, L, Clarke, S J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361225/
https://www.ncbi.nlm.nih.gov/pubmed/16552436
http://dx.doi.org/10.1038/sj.bjc.6603049