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Malignant melanoma and bone resorption

The cellular and humoral mechanisms accounting for osteolysis in skeletal metastases of malignant melanoma are uncertain. Osteoclasts, the specialised multinucleated cells that carry out bone resorption, are derived from monocyte/macrophage precursors. We isolated tumour-associated macrophages (TAMs...

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Detalles Bibliográficos
Autores principales: Lau, Y S, Sabokbar, A, Giele, H, Cerundolo, V, Hofstetter, W, Athanasou, N A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361270/
https://www.ncbi.nlm.nih.gov/pubmed/16641914
http://dx.doi.org/10.1038/sj.bjc.6603103