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Securin (hPTTG1) expression is regulated by β-catenin/TCF in human colorectal carcinoma
Overexpression of the transcriptional activator β-catenin, mostly owing to loss-of-function mutations of the adenomatous polyposis coli (APC) tumour suppressor gene, is crucial for the initiation and progression of human colorectal carcinogenesis. Securin is a regulator of chromosome separation and...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361298/ https://www.ncbi.nlm.nih.gov/pubmed/16705313 http://dx.doi.org/10.1038/sj.bjc.6603155 |