Restriction of GAGE protein expression to subpopulations of cancer cells is independent of genotype and may limit the use of GAGE proteins as targets for cancer immunotherapy

The GAGE cancer testis antigen gene family encodes products that can be recognized by autologous T cells, and GAGE proteins have been suggested as potential targets for cancer immunotherapy. Analysis of GAGE expression in tumours has primarily been performed at the level of gene transcription, where...

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Detalles Bibliográficos
Autores principales: Gjerstorff, M F, Johansen, L E, Nielsen, O, Kock, K, Ditzel, H J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361341/
https://www.ncbi.nlm.nih.gov/pubmed/16773077
http://dx.doi.org/10.1038/sj.bjc.6603163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361341/
https://www.ncbi.nlm.nih.gov/pubmed/16773077
http://dx.doi.org/10.1038/sj.bjc.6603163

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