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Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population

A substantial proportion of the familial risk of breast cancer may be attributable to genetic variants each contributing a small effect. pRb controls the cell cycle and polymorphisms within it are candidates for such low penetrance susceptibility alleles, since the gene has been implicated in severa...

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Detalles Bibliográficos
Autores principales: Lesueur, F, Song, H, Ahmed, S, Luccarini, C, Jordan, C, Luben, R, Easton, D F, Dunning, A M, Pharoah, P D, Ponder, B A J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361346/
https://www.ncbi.nlm.nih.gov/pubmed/16685266
http://dx.doi.org/10.1038/sj.bjc.6603160