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Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population
A substantial proportion of the familial risk of breast cancer may be attributable to genetic variants each contributing a small effect. pRb controls the cell cycle and polymorphisms within it are candidates for such low penetrance susceptibility alleles, since the gene has been implicated in severa...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361346/ https://www.ncbi.nlm.nih.gov/pubmed/16685266 http://dx.doi.org/10.1038/sj.bjc.6603160 |