Efaproxiral red blood cell concentration predicts efficacy in patients with brain metastases

Efaproxiral (Efaproxyn™, RSR13), a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O(2)) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. This analysis evaluated the Phase 3, Radiation Enhancing Allosteric Compound for Hypoxic Brain Metas...

Descripción completa

Detalles Bibliográficos
Autores principales: Stea, B, Shaw, E, Pintér, T, Hackman, J, Craig, M, May, J, Steffen, R P, Suh, J H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361352/
https://www.ncbi.nlm.nih.gov/pubmed/16773073
http://dx.doi.org/10.1038/sj.bjc.6603169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361352/
https://www.ncbi.nlm.nih.gov/pubmed/16773073
http://dx.doi.org/10.1038/sj.bjc.6603169

Ejemplares similares