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Efaproxiral red blood cell concentration predicts efficacy in patients with brain metastases

Efaproxiral (Efaproxyn™, RSR13), a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O(2)) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. This analysis evaluated the Phase 3, Radiation Enhancing Allosteric Compound for Hypoxic Brain Metas...

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Detalles Bibliográficos
Autores principales:	Stea, B, Shaw, E, Pintér, T, Hackman, J, Craig, M, May, J, Steffen, R P, Suh, J H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361352/ https://www.ncbi.nlm.nih.gov/pubmed/16773073 http://dx.doi.org/10.1038/sj.bjc.6603169

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