The Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomas

Our previous studies have implicated the Wnt antagonist, sFRP1, as a tumour suppressor gene in advanced colorectal cancer. In this study, we set out to investigate the relationship between sFRP1 expression and large bowel adenomas, a precursor of colorectal cancer. The induction of β-catenin/TCF med...

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Detalles Bibliográficos
Autores principales: Caldwell, G M, Jones, C E, Taniere, P, Warrack, R, Soon, Y, Matthews, G M, Morton, D G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361362/
https://www.ncbi.nlm.nih.gov/pubmed/16523202
http://dx.doi.org/10.1038/sj.bjc.6602967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361362/
https://www.ncbi.nlm.nih.gov/pubmed/16523202
http://dx.doi.org/10.1038/sj.bjc.6602967

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