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The α(2)β(1) integrin mediates the malignant phenotype on type I collagen in pancreatic cancer cell lines
Pancreatic cancer is characterised by a hallmark desmoplastic response that includes upregulated expression of the extracellular matrix, and type I collagen in particular. Recent studies indicate that pancreatic cancer cells stimulate type I collagen synthesis in adjacent stellate cells, and that th...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361410/ https://www.ncbi.nlm.nih.gov/pubmed/16622460 http://dx.doi.org/10.1038/sj.bjc.6603088 |