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The α(2)β(1) integrin mediates the malignant phenotype on type I collagen in pancreatic cancer cell lines

Pancreatic cancer is characterised by a hallmark desmoplastic response that includes upregulated expression of the extracellular matrix, and type I collagen in particular. Recent studies indicate that pancreatic cancer cells stimulate type I collagen synthesis in adjacent stellate cells, and that th...

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Detalles Bibliográficos
Autores principales: Grzesiak, J J, Bouvet, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361410/
https://www.ncbi.nlm.nih.gov/pubmed/16622460
http://dx.doi.org/10.1038/sj.bjc.6603088