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RNA interference as a key to knockdown overexpressed cyclooxygenase-2 gene in tumour cells

Silencing those genes that are overexpressed in cancer and contribute to the survival and progression of tumour cells is the aim of several researches. Cyclooxygenase-2 (COX-2) is one of the most intensively studied genes since it is overexpressed in most tumours, mainly in colon cancer. The use of...

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Detalles Bibliográficos
Autores principales: Strillacci, A, Griffoni, C, Spisni, E, Manara, M C, Tomasi, V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361412/
https://www.ncbi.nlm.nih.gov/pubmed/16622456
http://dx.doi.org/10.1038/sj.bjc.6603094