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Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition
p300 is a transcriptional cofactor and prototype histone acetyltransferase involved in regulating multiple cellular processes. We generated p300 deficient (p300(−)) cells from the colon carcinoma cell line HCT116 by gene targeting. Comparison of epithelial and mesenchymal proteins in p300(−) with pa...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361417/ https://www.ncbi.nlm.nih.gov/pubmed/16622451 http://dx.doi.org/10.1038/sj.bjc.6603101 |