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Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition

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p300 is a transcriptional cofactor and prototype histone acetyltransferase involved in regulating multiple cellular processes. We generated p300 deficient (p300(−)) cells from the colon carcinoma cell line HCT116 by gene targeting. Comparison of epithelial and mesenchymal proteins in p300(−) with pa...

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Detalles Bibliográficos
Autores principales:	Krubasik, D, Iyer, N G, English, W R, Ahmed, A A, Vias, M, Roskelley, C, Brenton, J D, Caldas, C, Murphy, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2006
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361417/ https://www.ncbi.nlm.nih.gov/pubmed/16622451 http://dx.doi.org/10.1038/sj.bjc.6603101

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