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Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis
Experimental evidence suggests that ageing-associated alterations in the tissue microenvironment act to promote prostate carcinogenesis. In this review, we survey the cellular state of senescence, review its causes, and describe associations with ageing and cancer. We further discuss senescent strom...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361445/ https://www.ncbi.nlm.nih.gov/pubmed/18182995 http://dx.doi.org/10.1038/sj.bjc.6604087 |