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A phase II study of paclitaxel and capecitabine as a first-line combination chemotherapy for advanced gastric cancer
Paclitaxel and capecitabine, which have distinct mechanisms of action and toxicity profiles, have each shown high activity as single agents in gastric cancer. Synergistic interaction between these two drugs was suggested by taxane-induced upregulation of thymidine phosphorylase. We, therefore, evalu...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361449/ https://www.ncbi.nlm.nih.gov/pubmed/18219288 http://dx.doi.org/10.1038/sj.bjc.6604186 |