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Safety, tolerability and pharmacokinetics of intravenous ghrelin for cancer-related anorexia/cachexia: a randomised, placebo-controlled, double-blind, double-crossover study
Twenty-one adult patients were randomised to receive ghrelin on days 1 and 8 and placebo on days 4 and 11 or vice versa, given intravenously over a 60-min period before lunch: 10 received 2 μg kg(−1) (lower-dose) ghrelin; 11 received 8 μg kg(−1) (upper-dose) ghrelin. Active and total ghrelin, growth...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361459/ https://www.ncbi.nlm.nih.gov/pubmed/18182992 http://dx.doi.org/10.1038/sj.bjc.6604148 |