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The endothelin B (ET(B)) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification

The vascular effects of the endothelin B (ET(B)) receptor agonist IRL 1620 were investigated in the rat P22 carcinosarcoma and a range of normal tissues in BDIX rats. Tissue blood flow rate was calculated from measurements of tissue uptake of radiolabelled iodoantipyrine. A comparison of vascular ef...

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Detalles Bibliográficos
Autores principales: Cemazar, M, Wilson, I, Prise, V E, Bell, K M, Hill, S A, Tozer, G M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361472/
https://www.ncbi.nlm.nih.gov/pubmed/15970923
http://dx.doi.org/10.1038/sj.bjc.6602672