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A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs

The quiescent cell population of tumours poses a barrier to the success of many cancer therapies. Most chemotherapeutic drugs target proliferating cells, but the growth fraction of many tumours is low. Based on the multicellular tumour spheroid model, a system was developed using human colon adenoca...

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Detalles Bibliográficos
Autores principales: Mellor, H R, Ferguson, D J P, Callaghan, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361565/
https://www.ncbi.nlm.nih.gov/pubmed/16052217
http://dx.doi.org/10.1038/sj.bjc.6602710