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A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs
The quiescent cell population of tumours poses a barrier to the success of many cancer therapies. Most chemotherapeutic drugs target proliferating cells, but the growth fraction of many tumours is low. Based on the multicellular tumour spheroid model, a system was developed using human colon adenoca...
Autores principales: | Mellor, H R, Ferguson, D J P, Callaghan, R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361565/ https://www.ncbi.nlm.nih.gov/pubmed/16052217 http://dx.doi.org/10.1038/sj.bjc.6602710 |
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