Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis

We recently reported that oxidative stress elicited by chronic inflammation increases the mutation of mitochondrial DNA (mtDNA) and possibly correlates with precancerous status. Since severe oxidative stress is elicited in the colorectal mucosa of individuals with ulcerative colitis (UC), the possib...

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Detalles Bibliográficos
Autores principales: Nishikawa, M, Oshitani, N, Matsumoto, T, Nishigami, T, Arakawa, T, Inoue, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361569/
https://www.ncbi.nlm.nih.gov/pubmed/15956973
http://dx.doi.org/10.1038/sj.bjc.6602664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361569/
https://www.ncbi.nlm.nih.gov/pubmed/15956973
http://dx.doi.org/10.1038/sj.bjc.6602664

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