Cargando…

Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis

We recently reported that oxidative stress elicited by chronic inflammation increases the mutation of mitochondrial DNA (mtDNA) and possibly correlates with precancerous status. Since severe oxidative stress is elicited in the colorectal mucosa of individuals with ulcerative colitis (UC), the possib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishikawa, M, Oshitani, N, Matsumoto, T, Nishigami, T, Arakawa, T, Inoue, M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361569/ https://www.ncbi.nlm.nih.gov/pubmed/15956973 http://dx.doi.org/10.1038/sj.bjc.6602664

Ejemplares similares

High expression of HSP47 in ulcerative colitis-associated carcinomas: proteomic approach
por: Araki, K, et al.
Publicado: (2009)

Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis
por: Hague, A, et al.
Publicado: (2005)

Mitochondrial DNA mutations in head and neck cancer are infrequent and lack prognostic utility
por: Challen, C, et al.
Publicado: (2011)

Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism
por: Meierhofer, D, et al.
Publicado: (2006)

Sequential expression of putative stem cell markers in gastric carcinogenesis
por: Wang, T, et al.
Publicado: (2011)

Raman spectroscopy: elucidation of biochemical changes in carcinogenesis of oesophagus
por: Shetty, G, et al.
Publicado: (2006)

KRAS-mutated plasma DNA as predictor of outcome from irinotecan monotherapy in metastatic colorectal cancer
por: Spindler, K G, et al.
Publicado: (2013)

Clinicopathological significance of mitochondrial D-Loop mutations in head and neck carcinoma
por: Lièvre, A, et al.
Publicado: (2006)

Early expression of the fractalkine receptor CX3CR1 in pancreatic carcinogenesis
por: Celesti, G, et al.
Publicado: (2013)

Mitochondrial D310 mutations in the early development of breast cancer
por: Xu, C, et al.
Publicado: (2012)

KRAS mutations in primary tumours and post-FOLFOX metastatic lesions in cases of colorectal cancer
por: Kawamoto, Y, et al.
Publicado: (2012)

BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer
por: Yokota, T, et al.
Publicado: (2011)

Nuclear survivin expression is associated with HPV-independent carcinogenesis and is an indicator of poor prognosis in oropharyngeal cancer
por: Preuss, S F, et al.
Publicado: (2008)

Very low prevalence of germline MSH6 mutations in hereditary non-polyposis colorectal cancer suspected patients with colorectal cancer without microsatellite instability
por: Kets, C M, et al.
Publicado: (2006)

Hypoxia-associated markers in gastric carcinogenesis and HIF-2α in gastric and gastro-oesophageal cancer prognosis
por: Griffiths, E A, et al.
Publicado: (2008)

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
por: Souglakos, J, et al.
Publicado: (2009)

BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection
por: Schirripa, M, et al.
Publicado: (2015)

Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations
por: Thirlwell, C, et al.
Publicado: (2007)

KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis
por: Deschoolmeester, V, et al.
Publicado: (2010)

Activation of nuclear factor-κB in human prostate carcinogenesis and association to biochemical relapse
por: Domingo-Domenech, J, et al.
Publicado: (2005)

Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
por: Nieminen, Mikko T, et al.
Publicado: (2018)

A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens
por: Gonzalez de Castro, D, et al.
Publicado: (2012)

Hypoxia-inducible factor-1α expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas
por: Griffiths, E A, et al.
Publicado: (2007)

KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients
por: Knijn, N, et al.
Publicado: (2011)

Network-based analysis of calcium-binding protein genes identifies Grp94 as a target in human oral carcinogenesis
por: Nomura, H, et al.
Publicado: (2007)

KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colorectal cancer
por: Renaud, S, et al.
Publicado: (2015)

TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy
por: Oden-Gangloff, A, et al.
Publicado: (2009)

Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liver
por: Wheelhouse, N M, et al.
Publicado: (2005)

Prevalence of somatic mitochondrial mutations and spatial distribution of mitochondria in non-small cell lung cancer
por: Kazdal, Daniel, et al.
Publicado: (2017)

BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients’ outcome
por: Saridaki, Z, et al.
Publicado: (2010)

Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms
por: Nishikawa, G, et al.
Publicado: (2013)

Pyrosequencing-based methods reveal marked inter-individual differences in oncogene mutation burden in human colorectal tumours
por: Weidlich, S, et al.
Publicado: (2011)

Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival
por: Kang, M K, et al.
Publicado: (2007)

Mitotic centromere-associated kinesin is a novel marker for prognosis and lymph node metastasis in colorectal cancer
por: Ishikawa, K, et al.
Publicado: (2008)

Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value
por: Lomnytska, M I, et al.
Publicado: (2011)

KRAS mutational status affects oxaliplatin-based chemotherapy independently from basal mRNA ERCC-1 expression in metastatic colorectal cancer patients
por: Basso, M, et al.
Publicado: (2013)

MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer
por: Ng, E K O, et al.
Publicado: (2009)

Specific mutations in KRAS codon 12 are associated with worse overall survival in patients with advanced and recurrent colorectal cancer
por: Jones, Robert P, et al.
Publicado: (2017)

Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer
por: Matsumoto, Akiko, et al.
Publicado: (2017)

Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients
por: Rawson, J B, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_akeec8e7tvl483sviqo3gia2pl