Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats

In spite of the clinical usefulness of cisplatin (CDDP), there are many occasions in which it is difficult to continue the administration of CDDP due to its nephrotoxicity and neurotoxicity. We examined the incorporation of CDDP into polymeric micelles to see if this allowed the resolution of these...

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Detalles Bibliográficos
Autores principales: Uchino, H, Matsumura, Y, Negishi, T, Koizumi, F, Hayashi, T, Honda, T, Nishiyama, N, Kataoka, K, Naito, S, Kakizoe, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361620/
https://www.ncbi.nlm.nih.gov/pubmed/16222314
http://dx.doi.org/10.1038/sj.bjc.6602772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361620/
https://www.ncbi.nlm.nih.gov/pubmed/16222314
http://dx.doi.org/10.1038/sj.bjc.6602772

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