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Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia

Muscle protein degradation is thought to play a major role in muscle atrophy in cancer cachexia. To investigate the importance of the ubiquitin-proteasome pathway, which has been suggested to be the main degradative pathway mediating progressive protein loss in cachexia, the expression of mRNA for p...

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Detalles Bibliográficos
Autores principales: Khal, J, Wyke, S M, Russell, S T, Hine, A V, Tisdale, M J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361629/
https://www.ncbi.nlm.nih.gov/pubmed/16160695
http://dx.doi.org/10.1038/sj.bjc.6602780