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Endostatin expression in a pancreatic cell line is modulated by a TNFα-dependent elastase

Endostatin, an inhibitor of angiogenesis, is a 20 kDa fragment of the basement membrane protein, collagen XVIII. The formation of endostatin relies upon the action of proteases on collagen XVIII. TNFα, produced by activated macrophages, is a multifunctional proinflammatory cytokine with known effect...

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Detalles Bibliográficos
Autores principales: Brammer, R D, Bramhall, S R, Eggo, M C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361670/
https://www.ncbi.nlm.nih.gov/pubmed/16234817
http://dx.doi.org/10.1038/sj.bjc.6602835