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Endostatin expression in a pancreatic cell line is modulated by a TNFα-dependent elastase
Endostatin, an inhibitor of angiogenesis, is a 20 kDa fragment of the basement membrane protein, collagen XVIII. The formation of endostatin relies upon the action of proteases on collagen XVIII. TNFα, produced by activated macrophages, is a multifunctional proinflammatory cytokine with known effect...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361670/ https://www.ncbi.nlm.nih.gov/pubmed/16234817 http://dx.doi.org/10.1038/sj.bjc.6602835 |