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p53 polymorphisms associated with mutations in and loss of heterozygosity of the p53 gene in male oral squamous cell carcinomas in Taiwan

The present study was designed to examine whether different p53 haplotypes of exon 4–intron 3–intron 6 affect the frequency of mutations and loss of heterozygosity (LOH) of the p53 gene in male oral squamous cell carcinomas (OSCCs) in Taiwan. We found that individuals without two Pro-W-G alleles had...

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Detalles Bibliográficos
Autores principales: Hsieh, L-L, Huang, T-H, Chen, I-H, Liao, C-T, Wang, H-M, Lai, C-H, Liou, S-H, Chang, J T-C, Cheng, A-J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361746/
https://www.ncbi.nlm.nih.gov/pubmed/15583690
http://dx.doi.org/10.1038/sj.bjc.6602271